Biological tools enable researchers to discover new reactions from complex mixtures of different substrates.
References
Kanan, M.W., Rozenman, M.M., Sakurai, K., Snyder, T.M. & Liu, D.R. Nature 431, 545–549 (2004).
Stambuli, J.P. & Hartwig, J.F. Curr. Opin. Chem. Biol. 7, 420–426 (2003).
Reetz, M.T. Angew. Chem. Int. Ed. 40, 284–310 (2001).
Evans, C.A. & Miller, S.J. Curr. Opin. Chem. Biol. 6, 333–338 (2002).
Breslow, R. Acc. Chem. Res. 28, 146–153 (1995).
Schultz, P.G. & Lerner, R.A. Nature 418, 485 (2002).
Trost, B.M. Acc. Chem. Res. 35, 695–705 (2002).
Nicoloau, K.C. Angew. Chem. Int. Ed. 39, 44–122 (2000).
Schreiber, S.L. Science 287, 1964–1969 (2000).
Anasta, P.T. & Kirchoff, M.M. Acc. Chem. Res. 35, 686–694 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Miller, S. DNA as a template for reaction discovery. Nat Biotechnol 22, 1378–1379 (2004). https://doi.org/10.1038/nbt1104-1378
Issue Date:
DOI: https://doi.org/10.1038/nbt1104-1378
- Springer Nature America, Inc.