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Tracing cancer networks with phosphoproteomics

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A mass-spectrometry approach for identifying downstream events in cancer signaling pathways may help to tailor therapies to individual patients.

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Figure 1: Identification of (Ser)/(Thr) phosphorylation substrates in core cancer signaling pathways.

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Authors and Affiliations

  1. David B. Solit and Ingo K. Mellinghoff are in the Human Oncology and Pathogenesis Program, Memorial Sloan-Kettering Cancer Center, New York, New York, USA.,

    David B Solit & Ingo K Mellinghoff

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  1. David B Solit
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  2. Ingo K Mellinghoff
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Correspondence to David B Solit or Ingo K Mellinghoff.

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The authors declare no competing financial interests.

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Solit, D., Mellinghoff, I. Tracing cancer networks with phosphoproteomics. Nat Biotechnol 28, 1028–1029 (2010). https://doi.org/10.1038/nbt1010-1028

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