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Keeping dry and crossing membranes

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Figure 1: Wrapping of the glucagon molecule in helical conformation (PDB entry 1GCN).
Figure 2: Time dependence of the adsorption uptake and desorption of soluble mutants of the G4V glucagon peptide onto and from a dilauryl phosphatidylcholine bilayer coating a biosensing optical device.

Bob Crimi

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Acknowledgements

This research was supported in part by an unrestricted grant from Eli Lilly and Company. The work was motivated by conversations with Richard DiMarchi.

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Authors and Affiliations

  1. Indiana University School of Informatics and Center for Computational Biology and Bioinformatics, Indiana University Medical School, 714 N. Senate Avenue, Indianapolis, 46202, Indiana, USA

    Ariel Fernández

  2. Department of Computer Science, The University of Chicago, Chicago, 60637, Illinois, USA

    Ariel Fernández

  3. Institute for Protein Research, Osaka University, Yamadaoka 3-2, Suita, Osaka, 565-0871, Japan

    Ariel Fernández

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  1. Ariel Fernández
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Fernández, A. Keeping dry and crossing membranes. Nat Biotechnol 22, 1081–1084 (2004). https://doi.org/10.1038/nbt0904-1081

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