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Paring down signaling complexity

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A new method for characterizing signaling responses to pairs of agonists predicts how cells react to higher-order combinations of external stimuli.

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Figure 1: Combining pairwise agonist scanning (PAS) with neural-network modeling to capture a complex stimulus landscape.

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Authors and Affiliations

  1. Kevin A. Janes is in the Department of Biomedical Engineering, University of Virginia, Charlottesville, Virginia, USA.,

    Kevin A Janes

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  1. Kevin A Janes
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Correspondence to Kevin A Janes.

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The author declares no competing financial interests.

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Janes, K. Paring down signaling complexity. Nat Biotechnol 28, 681–682 (2010). https://doi.org/10.1038/nbt0710-681

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