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Human embryonic stem cells flock together

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An international survey of human embryonic stem cell lines provides a benchmark for comparing results across laboratories.

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Figure 1: The International Stem Cell Initiative (ISCI) compared 59 different hES cell lines using a set of standardized metrics including: surface antigens, gene expression, imprinting status, microbiological purity, and in many cases, in vivo differentiation potential (teratoma-like xenografts).

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Authors and Affiliations

  1. M. William Lensch and George Q. Daley are in the Division of Hematology/Oncology, MA 02115 Department of Biological Chemistry and Molecular Pharmacology, Children's Hospital Boston, Karp Building, 7th Floor 300 Longwood Ave. Boston, Harvard Medical School, Boston, Massachusetts and Harvard Stem Cell Institute, Cambridge, Massachusetts, USA. George.Daley@childrens.harvard.edu,

    M William Lensch & George Q Daley

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  1. M William Lensch
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  2. George Q Daley
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Lensch, M., Daley, G. Human embryonic stem cells flock together. Nat Biotechnol 25, 748–750 (2007). https://doi.org/10.1038/nbt0707-748

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