Skip to main content

Advertisement

SpringerLink
Log in

Vectorology recapitulates virology—will it capitulate oncology?

  • News & Views
  • Published:

From Nature Biotechnology

View current issue Submit your manuscript

Tumor-selective stabilization of RNA is employed as a new approach to engineer viruses that preferentially replicate in cancer cells.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Figure 1: General oncolytic virus theory and models.

©Rebecca Henretta

References

  1. Ahmed, A. et al. Nat. Biotechnol. 21, 771–777 (2003).

    Article  CAS  Google Scholar 

  2. Smith, R. et al. Cancer 9, 1211–1218 (1956).

    Article  Google Scholar 

  3. Kirn, D. Oncogene 19, 6660–6669 (2000).

    Article  CAS  Google Scholar 

  4. Chiocca, E.A. Nat. Rev. Cancer 2, 938–951 (2002).

    Article  Google Scholar 

  5. Mullen, J.T. & Tanabe, K.K. The Oncologist 7, 106–119 (2002).

    Article  CAS  Google Scholar 

  6. Knipe, D.M. & Howley, P.M. (eds.). Fields Virology (Lippincott Williams & Wilkins, Philadelphia, Pennsylvania, USA, 2001).

    Google Scholar 

  7. Raghavan, A. et al. Nucleic Acids Res. 30, 5529–5538 (2002).

    Article  CAS  Google Scholar 

  8. Cumming, S.A. J. Virol. 76, 5993–6003 (2002).

    Article  CAS  Google Scholar 

  9. Nabors, L.B., Gillespie, G.Y., Harkins, L. & King, P.H. Cancer Res. 61, 2154–2161 (2001).

    CAS  PubMed  Google Scholar 

  10. Wein, M.L., Wu, J.T. & Kirn, D.H. Cancer Res. 63, 1317–1324 (2003).

    CAS  PubMed  Google Scholar 

  11. Harrison, D. et al. Hum. Gene Ther. 12, 1323–1332 (2001).

    Article  CAS  Google Scholar 

  12. Wakimoto, H., Johnson, P.R., Knipe, D.M. & Chiocca, E.A. Gene Ther. 10, 983–999 (2003).

    Article  CAS  Google Scholar 

  13. Toth, K. et al. Mol. Ther. 7, 435–437 (2003).

    Article  CAS  Google Scholar 

  14. Freytag, S. et al. Cancer Res. 62, 4968–4976 (2002).

    CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. The author is at Advantagene, 160 Paulson Rd., Waban, 02468, MA, USA

    Estaurdo Aguilar-Cordova

Authors
  1. Estaurdo Aguilar-Cordova
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Aguilar-Cordova, E. Vectorology recapitulates virology—will it capitulate oncology?. Nat Biotechnol 21, 756–757 (2003). https://doi.org/10.1038/nbt0703-756

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt0703-756

  • Springer Nature America, Inc.

Search

Navigation