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No longer lost in translation

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Two in vivo real-time single molecule assays demonstrate that stochastic gene expression results in punctuated bursts of protein synthesis.

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Figure 1: Two approaches to monitor fluorescent bursts of protein synthesis in E. coli. Both use the lac promoter under conditions that support low levels of transcription.

Bob Crimi

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Cooperman, B., Goldman, Y. No longer lost in translation. Nat Biotechnol 24, 526–527 (2006). https://doi.org/10.1038/nbt0506-526

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