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Reality and immortality—neural stem cells for therapies

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The successful immortalization of neural progenitor cells via the overexpression of telomerase prompts several questions for those intending to develop somatic stem cell therapies for neurological disease.

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Figure 1: Neural stem and progenitor cells: production, therapy and safety concerns.

Bob Crimi

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Authors and Affiliations

  1. Department of Neurology at Johns Hopkins University, Meyer 6-109, 600 N. Wolfe St., Baltimore, 21287, Maryland, USA

    Jeffrey D Rothstein

  2. Director of the Program in Developmental and Regenerative Cell Biology, The Burnham Institute, 10901 North Torrey Pines Road, La Jolla, 92037, California, USA

    Evan Y Snyder

Authors
  1. Jeffrey D Rothstein
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  2. Evan Y Snyder
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Rothstein, J., Snyder, E. Reality and immortality—neural stem cells for therapies. Nat Biotechnol 22, 283–285 (2004). https://doi.org/10.1038/nbt0304-283

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