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Ontology engineering

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Figure 1
Figure 2: Three-dimensional evolution of GO over ten releases from 2005 to 2007 along the three dimensions of structural inefficiency.

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Acknowledgements

This work was supported in part by the National Library of Medicine (NLM/NIH) under grants 1K99LM009826 and 5T15LM007092 and by the National Human Genome Research Institute (NHGRI/NIH) under grants 2P41HG02273, 1R01HG003354, and 1R01HG004836. The authors are grateful to the anonymous reviewers for their helpful suggestions.

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Authors and Affiliations

  1. Harvard-MIT Division of Health Sciences and Technology, Children's Hospital Informatics Program, Harvard Medical School, Boston, Massachusetts, USA

    Gil Alterovitz, Michael Xiang, Jonathan Dreyfuss & Marco F Ramoni

  2. Partners Healthcare Center for Personalized Genetic Medicine, Boston, Massachusetts, USA

    Gil Alterovitz, Michael Xiang, Michael Cherkassky, Jonathan Dreyfuss & Marco F Ramoni

  3. Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Gil Alterovitz

  4. Jackson Laboratory, Bar Harbor, Maine, USA

    David P Hill, Mary E Dolan & Judith A Blake

  5. EMBL-EBI, Wellcome Trust Genome Campus, Hinxton, UK

    Jane Lomax & Midori A Harris

  6. Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA

    Jonathan Liu

  7. Lawrence Berkeley National Laboratory, Berkeley, California, USA

    Chris Mungall

Authors
  1. Gil Alterovitz
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  2. Michael Xiang
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  3. David P Hill
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  9. Midori A Harris
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  10. Mary E Dolan
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  11. Judith A Blake
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  12. Marco F Ramoni
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Corresponding authors

Correspondence to Gil Alterovitz or Marco F Ramoni.

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The authors declare no competing financial interests.

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Supplementary Notes 1–8 and Supplementary Table 1 (PDF 223 kb)

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Alterovitz, G., Xiang, M., Hill, D. et al. Ontology engineering. Nat Biotechnol 28, 128–130 (2010). https://doi.org/10.1038/nbt0210-128

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