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Sequencing in real time

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DNA synthesis by single polymerase molecules has been visualized at the speed of catalysis, heralding a new sequencing technology of unparalleled throughput.

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Figure 1: Real-time single-molecule sequencing.

Kim Caesar

References

  1. Metzker, M.L. Genome Res. 15, 1767–1776 (2005).

    Article  CAS  Google Scholar 

  2. Eid, J. et al. Science 323, 133–138 (2009).

    Article  CAS  Google Scholar 

  3. Margulies, M. et al. Nature 437, 376–380 (2005).

    Article  CAS  Google Scholar 

  4. Bentley, D.R. et al. Nature 456, 53–59 (2008).

    Article  CAS  Google Scholar 

  5. Valouev, A. et al. Genome Res. 18, 1051–1063 (2008).

    Article  CAS  Google Scholar 

  6. Harris, T.D. et al. Science 320, 106–109 (2008).

    Article  CAS  Google Scholar 

  7. Levene, M.J. et al. Science 299, 682–686 (2003).

    Article  CAS  Google Scholar 

  8. Soengas, M.S., Gutiérrez, C. & Salas, M. J. Mol. Biol. 253, 517–529 (1995).

    Article  CAS  Google Scholar 

Download references

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Metzker, M. Sequencing in real time. Nat Biotechnol 27, 150–151 (2009). https://doi.org/10.1038/nbt0209-150

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