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Single-minded CRISPR screening

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Transcriptome-wide effects of gene knockouts are screened at the single-cell level by combining high-throughput, single-cell RNA-seq with lentiviral CRISPR libraries.

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Figure 1: Pooled CRISPR screening strategies.

Marina Corral Spence / Springer Nature

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Authors and Affiliations

  1. Cold Spring Harbor Laboratory, Cold Spring Harbor, New York, USA

    Bryan R Lanning & Christopher R Vakoc

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  1. Bryan R Lanning
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  2. Christopher R Vakoc
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Correspondence to Christopher R Vakoc.

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Competing interests

Christopher Vakoc is an advisor to KSQ therapeutics.

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Lanning, B., Vakoc, C. Single-minded CRISPR screening. Nat Biotechnol 35, 339–340 (2017). https://doi.org/10.1038/nbt.3849

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