Despite recent failures, a flurry of activity in biotech and pharma is raising hopes that an effective drug for this fatal lung disease is on the way. Ken Garber investigates.
References
Noble, P.W. et al. Lancet 377, 1760–1769 (2011).
Raghu, G. et al. Am. J. Respir. Crit. Care Med. 183, 788–824 (2011).
Barry-Hamilton, V. et al. Nat. Med. 16, 1009–1017 (2010).
Tager, A.M. et al. Nat. Med. 14, 45–54 (2008).
Richeldi, L. et al. N. Engl. J. Med. 365, 1079–1087 (2011).
Maher, T.M. Eur. Respir. Rev. 22, 148–152 (2013).
Idiopathic Pulmonary Fibrosis Clinical Research Network. N. Engl. J. Med. 366, 1968–1977 (2012).
Van Den Blink, B. et al. American Thoracic Society meeting abstract A5707 (2013).
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At the frontiers of lung fibrosis therapy. Nat Biotechnol 31, 781–783 (2013). https://doi.org/10.1038/nbt.2687
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DOI: https://doi.org/10.1038/nbt.2687
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