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White matter from fibroblasts

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Myelinating oligodendrocytes are induced from murine embryonic fibroblasts by transcription factor–mediated reprogramming.

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Figure 1: Murine embryonic fibroblasts are reprogrammed by transduction with one of three sets of transcription factors to generate induced oligodendrocyte progenitor cells (iOPCs) without a pluripotent intermediary.

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Authors and Affiliations

  1. Steven A. Goldman is in the Center for Translational Neuromedicine and the Department of Neurology at the University of Rochester Medical Center, Rochester, New York, USA.,

    Steven A Goldman

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  1. Steven A Goldman
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Correspondence to Steven A Goldman.

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The author declares no competing financial interests.

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Goldman, S. White matter from fibroblasts. Nat Biotechnol 31, 412–413 (2013). https://doi.org/10.1038/nbt.2570

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