The Cas9 endonuclease is reprogrammed by RNAs for site-specific modification of eukaryotic and microbial genomes.
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Mussolino, C., Cathomen, T. RNA guides genome engineering. Nat Biotechnol 31, 208–209 (2013). https://doi.org/10.1038/nbt.2527
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DOI: https://doi.org/10.1038/nbt.2527
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