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First CHO genome

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An ancestor of the Chinese hamster ovary cell lines used for production of recombinant therapeutics has been sequenced.

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Figure 1: Genetic heterogeneity of CHO cell lines.

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Authors and Affiliations

  1. Florian M. Wurm and David Hacker are at the Swiss Federal Institute of Technology Lausanne (EPFL), Faculty of Life Sciences and Faculty of Basic Sciences, Laboratory of Cellular Biotechnology, Lausanne, Switzerland.,

    Florian M Wurm & David Hacker

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  1. Florian M Wurm
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  2. David Hacker
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Correspondence to Florian M Wurm.

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The authors declare no competing financial interests.

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Wurm, F., Hacker, D. First CHO genome. Nat Biotechnol 29, 718–720 (2011). https://doi.org/10.1038/nbt.1943

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