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SiRNA delivery with exosome nanoparticles

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A natural system for ferrying RNA between cells is used to transport siRNA to the mouse brain.

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Figure 1: Advantages and drawbacks of siRNA delivery by exosomes, viruses, lipid nanoparticles or polymeric nanoparticles.

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Authors and Affiliations

  1. Jasper G. van den Boorn, Martin Schlee, Christoph Coch and Gunther Hartmann are at the Institute for Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany.,

    Jasper G van den Boorn, Martin Schlee, Christoph Coch & Gunther Hartmann

Authors
  1. Jasper G van den Boorn
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  2. Martin Schlee
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  3. Christoph Coch
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  4. Gunther Hartmann
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Correspondence to Gunther Hartmann.

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The authors declare no competing financial interests.

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van den Boorn, J., Schlee, M., Coch, C. et al. SiRNA delivery with exosome nanoparticles. Nat Biotechnol 29, 325–326 (2011). https://doi.org/10.1038/nbt.1830

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