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Cancer

Tumours addicted to drugs are vulnerable

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Cancer cells can develop an 'addiction' to the drugs they are treated with, so that they need the drugs to survive. Analysis of the underlying mechanism reveals a potential clinical strategy for harnessing this phenomenon. See Letter p.270

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Figure 1: Drug addiction in cancer cells.

References

  1. Das Thakur, M. et al. Nature 494, 251–255 (2013).

    Article  ADS  CAS  Google Scholar 

  2. Kong, X. et al. Nature 550, 270–274 (2017).

    Article  ADS  Google Scholar 

  3. Hoek, K. S. et al. Cancer Res. 68, 650–656 (2008).

    Article  CAS  Google Scholar 

  4. Müller, J. et al. Nature Commun. 5, 5712 (2014).

    Article  ADS  Google Scholar 

  5. Garraway, L. A. et al. Nature 436, 117–122 (2005).

    Article  ADS  CAS  Google Scholar 

  6. Schreuer, M. et al. Lancet Oncol. 18, 464–472 (2017).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. Molecular Oncology Group, Cancer Research UK Manchester Institute, Manchester, M20 4BX, UK

    Rebecca J. Lee & Richard Marais

  2. Faculty of Biology, Medicine and Health, The University of Manchester,

    Rebecca J. Lee & Richard Marais

Authors
  1. Rebecca J. Lee
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  2. Richard Marais
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Corresponding author

Correspondence to Richard Marais.

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Lee, R., Marais, R. Tumours addicted to drugs are vulnerable. Nature 550, 192–193 (2017). https://doi.org/10.1038/nature24148

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