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DNA repair

Telomere-lengthening mechanism revealed

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Shortening of the ends of chromosomes limits a cell's lifespan. Some cancer cells avoid this fate through a mechanism called alternative lengthening of telomeres, molecular details of which have now been defined. See Article p.54

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Figure 1: Break-induced telomere synthesis.

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Authors and Affiliations

  1. Caitlin M. Roake and Steven E. Artandi are in the Departments of Medicine and of Biochemistry and the Cancer Biology Program, Stanford University School of Medicine, Stanford, California 94305, USA.,

    Caitlin M. Roake & Steven E. Artandi

Authors
  1. Caitlin M. Roake
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  2. Steven E. Artandi
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Correspondence to Steven E. Artandi.

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Roake, C., Artandi, S. Telomere-lengthening mechanism revealed. Nature 539, 35–36 (2016). https://doi.org/10.1038/nature19483

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