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In search of the memory molecule

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The protein PKM-ζ has been proposed to regulate the maintenance of memory in rodents, but this theory has been questioned. The finding that another isoform of the protein acts as a backup if PKM-ζ is lacking will influence this debate.

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Figure 1: Memory loss modulated.

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Authors and Affiliations

  1. Canada. They are also in the Departments of Physiology and Psychology and at the Institute of Medical Science, Paul W. Frankland and Sheena A. Josselyn are in the Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario M5G 1X8, University of Toronto, Toronto.,

    Paul W. Frankland & Sheena A. Josselyn

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  1. Paul W. Frankland
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  2. Sheena A. Josselyn
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Frankland, P., Josselyn, S. In search of the memory molecule. Nature 535, 41–42 (2016). https://doi.org/10.1038/nature18903

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