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When sperm meets egg

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Sperm–egg binding is mediated by two cell-surface proteins. Structural analysis of these proteins separately and in complex provides insight into the recognition process and the subsequent sperm–egg fusion. See Letters p.562 & p.566

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Figure 1: Juno stabilizes the Izumo1 hinge.

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Authors and Affiliations

  1. Karsten Melcher is at the Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.,

    Karsten Melcher

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  1. Karsten Melcher
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Correspondence to Karsten Melcher.

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Melcher, K. When sperm meets egg. Nature 534, 484–485 (2016). https://doi.org/10.1038/nature18448

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