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Cell reprogramming

Brain versus brawn

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The mechanisms that underlie enforced transitions between mature cell lineages are poorly understood. Profiling single skin cells that are induced to become neurons reveals that, unexpectedly, they often become muscle. See Letter p.391

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Figure 1: A tug-of-war between cell types.

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Authors and Affiliations

  1. Bruno Di Stefano and Konrad Hochedlinger are in the Department of Molecular Biology, and in the Department of Stem Cell and Regenerative Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA, Harvard University and Harvard Medical School, and the Harvard Stem Cell Institute, Cambridge, Massachusetts.,

    Bruno Di Stefano & Konrad Hochedlinger

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  1. Bruno Di Stefano
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  2. Konrad Hochedlinger
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Correspondence to Konrad Hochedlinger.

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Di Stefano, B., Hochedlinger, K. Brain versus brawn. Nature 534, 332–333 (2016). https://doi.org/10.1038/nature18444

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