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Organelle stress triggers inflammation

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The intracellular NOD1 and NOD2 receptors have been found to activate innate inflammation when a condition known as endoplasmic reticulum stress is induced by bacterial infection. See Letter p.394

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Figure 1: NOD proteins respond to infection through distinct pathways.

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Authors and Affiliations

  1. Bennett H. Penn is in the Department of Medicine, Division of Infectious Diseases, University of California, San Francisco, San Francisco, California 94143, USA.,

    Bennett H. Penn

  2. Jeffery S. Cox is in the Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720-3370, USA.,

    Jeffery S. Cox

Authors
  1. Bennett H. Penn
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  2. Jeffery S. Cox
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Correspondence to Bennett H. Penn or Jeffery S. Cox.

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Penn, B., Cox, J. Organelle stress triggers inflammation. Nature 532, 321–322 (2016). https://doi.org/10.1038/nature17882

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