The finding that acute and chronic manipulations of the same neural circuit can produce different behavioural outcomes poses new questions about how best to analyse these circuits. See Article p.358
This is a preview of subscription content, log in via an institution to check access.
Notes
References
Emiliani, V., Cohen, A. E., Deisseroth, K. & Häusser, M. J. Neurosci. 35, 13917–13926 (2015).
Otchy, T. M. et al. Nature 528, 358–363 (2015).
Kawai, R. et al. Neuron 86, 800–812 (2015).
Johansen, J. P., Wolff, S. B., Lüthi, A. & LeDoux, J. E. Biol. Psychiatry 71, 1053–1060 (2012).
Squire, L. R., Genzel, L., Wixted, J. T. & Morris, R. G. Cold Spring Harb. Perspect. Biol. 7, a021766 (2015).
Rothwell, P. E. et al. Cell 158, 198–212 (2014).
Buetfering, C., Allen, K. & Monyer, H. Nature Neurosci. 17, 710–718 (2014).
Chaumont, J. et al. Proc. Natl Acad. Sci. USA 110, 16223–16228 (2013).
Kravitz, A. V., Owen, S. F. & Kreitzer, A. C. Brain Res. 1511, 21–32 (2013).
Author information
Authors and Affiliations
Corresponding author
Related links
Rights and permissions
About this article
Cite this article
Südhof, T. Experimental mismatch in neural circuits. Nature 528, 338–339 (2015). https://doi.org/10.1038/nature16323
Published:
Issue Date:
DOI: https://doi.org/10.1038/nature16323
- Springer Nature Limited
This article is cited by
-
A neural network for intermale aggression to establish social hierarchy
Nature Neuroscience (2018)
-
Motor cortex — to act or not to act?
Nature Reviews Neuroscience (2017)