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Antibodies regulate antitumour immunity

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Boosting the T cells that mediate anticancer immune responses is a therapeutic goal. But T cells do not work alone — B cells and the antibodies they produce can both trigger and suppress the response. See Letters p.94 & p.99

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Figure 1: Two opposing roles for B cells in cancer immunology.

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Authors and Affiliations

  1. Laurence Zitvogel is at the Gustave Roussy Comprehensive Cancer Center, 94805 Villejuif, France.,

    Laurence Zitvogel

  2. Guido Kroemer is at the Cordeliers Research Center of the University Paris Descartes, 75006 Paris, France, and at the Pôle de Biologie, Hôpital Européen Georges Pompidou, Paris.,

    Guido Kroemer

Authors
  1. Laurence Zitvogel
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  2. Guido Kroemer
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Correspondence to Guido Kroemer.

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Zitvogel, L., Kroemer, G. Antibodies regulate antitumour immunity. Nature 521, 35–37 (2015). https://doi.org/10.1038/nature14388

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