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Structural biology

Ribosome revelations

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Proteins are synthesized in cells by the ribosome apparatus. A report of 16 yeast ribosome structures, each bound by a different inhibitor, broadens our understanding of how drugs affect ribosome activity. See Article p.517

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Figure 1: Binding sites of protein-translation inhibitors in the yeast ribosome.

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Authors and Affiliations

  1. Nelson B. Olivier is in the Innovative Medicines and Early Development Unit, AstraZeneca Pharmaceuticals, Cambridge Science Park, Cambridge CB4 0FZ, UK.,

    Nelson B. Olivier

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  1. Nelson B. Olivier
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Correspondence to Nelson B. Olivier.

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Olivier, N. Ribosome revelations. Nature 513, 491–492 (2014). https://doi.org/10.1038/nature13747

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