Mice deficient in the EDA protein lack normal tooth features. Restoring EDA in embryonic teeth at increasing doses has now been found to recover these dental features in a stepwise pattern that mimics evolution. See Article p.44
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Luo, ZX. Tooth structure re-engineered. Nature 512, 36–37 (2014). https://doi.org/10.1038/nature13651
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DOI: https://doi.org/10.1038/nature13651
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