The early development of acute leukaemias is assumed for the most part to be clinically silent and transient. But it now seems that ancestral precancerous cells are identifiable and persistent. See Article p.328
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Potter, N., Greaves, M. Persistence of leukaemic ancestors. Nature 506, 300–301 (2014). https://doi.org/10.1038/nature13056
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DOI: https://doi.org/10.1038/nature13056
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