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Molecular biology

The tug of DNA repair

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The transcription enzyme RNA polymerase stalls at DNA lesions, hindering their repair. Accessory factors dislodge the enzyme by pushing it forwards, but a study finds that pulling it backwards may also be effective. See Article p.372

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Figure 1: Alternative routes for transcription-coupled repair in bacteria.

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Authors and Affiliations

  1. Irina Artsimovitch is in the Department of Microbiology and the Center for RNA Biology, Ohio State University, Columbus, Ohio 43210, USA.,

    Irina Artsimovitch

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  1. Irina Artsimovitch
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Correspondence to Irina Artsimovitch.

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Artsimovitch, I. The tug of DNA repair. Nature 505, 298–299 (2014). https://doi.org/10.1038/nature12850

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