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Drug discovery

Pocket of opportunity

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After three decades of unsuccessful efforts to develop small molecules that neutralize the cancer-causing Ras proteins, an approach has been found that opens up fresh avenues for anticancer research. See Letter p.548

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Figure 1: Binding pockets for Ras inhibitors.

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Authors and Affiliations

  1. Gideon Bollag and Chao Zhang are at Plexxikon Inc., Berkeley, California 94710, USA.,

    Gideon Bollag & Chao Zhang

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  1. Gideon Bollag
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  2. Chao Zhang
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Correspondence to Gideon Bollag or Chao Zhang.

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Bollag, G., Zhang, C. Pocket of opportunity. Nature 503, 475–476 (2013). https://doi.org/10.1038/nature12835

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