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Antibiotics

Killing the survivors

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Antibiotic-tolerant, dormant variants of otherwise antibiotic-sensitive bacteria underlie many chronic and relapsing infections. A small molecule has been identified that can efficiently eradicate these persister cells. See Article p.365

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Figure 1: ADEPs activate ClpP and kill persister bacteria.

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Authors and Affiliations

  1. and in the Department of Biology, Kenn Gerdes is at the Centre for Bacterial Cell Biology, Institute for Cell and Molecular Biosciences, Newcastle University, Newcastle upon Tyne NE2 4AX, UK, University of Copenhagen, Denmark.,

    Kenn Gerdes

  2. Hanne Ingmer is in the Department of Veterinary Disease Biology, University of Copenhagen, 1870 Frederiksberg, Denmark.,

    Hanne Ingmer

Authors
  1. Kenn Gerdes
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  2. Hanne Ingmer
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Correspondence to Kenn Gerdes or Hanne Ingmer.

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Gerdes, K., Ingmer, H. Killing the survivors. Nature 503, 347–349 (2013). https://doi.org/10.1038/nature12834

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