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Metal ghosts in the splicing machine

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Chemical analysis of the spliceosome's active site reveals that it is the RNA components of this enzyme complex that coordinate the catalytic metal ions responsible for production of a spliced messenger RNA. See Article p.229

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Figure 1: Active sites of group II introns and the spliceosome.

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Authors and Affiliations

  1. Scott A. Strobel is in the Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, Connecticut 06520, USA.,

    Scott A. Strobel

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  1. Scott A. Strobel
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Correspondence to Scott A. Strobel.

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Strobel, S. Metal ghosts in the splicing machine. Nature 503, 201–202 (2013). https://doi.org/10.1038/nature12705

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