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Multiple sclerosis

An old drug plays a new trick

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A drug already used to treat Parkinson's disease induces repair of the damage that occurs to the myelin sheath around nerve fibres during multiple sclerosis. The finding offers new therapeutic avenues for this disease. See Article p.327

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Figure 1: Identification of a myelin-promoting drug.

Notes

  1. *This article and the paper under discussion2 were published online on 9 October 2013.

References

  1. Hauser, S. L., Chan, J. R. & Oksenberg, J. R. Ann. Neurol. 74, 317–327 (2013).

    Article  CAS  Google Scholar 

  2. Deshmukh, V. et al. Nature 502, 327–332 (2013).

    Article  ADS  CAS  Google Scholar 

  3. Burgyone, K., Aduri, K., Ananth, J. & Parameswaran, S. Curr. Pharm. Des. 10, 2239–2248 (2004).

    Article  CAS  Google Scholar 

  4. De Angelis, F., Bernardo, A., Magnaghi, V., Minghetti, L. & Tata, A. M. Dev. Neurobiol. 72, 713–728 (2012).

    Article  CAS  Google Scholar 

  5. Gold, R., Linington, C. & Lassmann, H. Brain 129, 1953–1971 (2006).

    Article  Google Scholar 

  6. Ludwin, S. K. Lab. Invest. 43, 382–387 (1980).

    CAS  PubMed  Google Scholar 

  7. Franklin, R. J. M. & Ffrench-Constant, C. Nature Rev. Neurosci. 9, 839–855 (2008).

    Article  CAS  Google Scholar 

  8. Patrikios, P. et al. Brain 129, 3165–3172 (2006).

    Article  Google Scholar 

  9. Chang, A., Tourtellotte, W. W., Rudick, R. & Trapp, B. D. N. Engl. J. Med. 346, 165–173 (2002).

    Article  Google Scholar 

  10. Jacobs, L. & Johnson, K. P. Arch. Neurol. 51, 1245–1252 (1994).

    Article  CAS  Google Scholar 

  11. Steinman, L. Science 305, 212–216 (2004).

    Article  ADS  CAS  Google Scholar 

  12. Nicholas, R., Young, C. & Friede, T. Expert Opin. Drug Safety 9, 905–915 (2010).

    Article  Google Scholar 

  13. van der Walt, A. et al. Pharmacol. Ther. 126, 82–93 (2010).

    Article  CAS  Google Scholar 

Download references

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Authors and Affiliations

  1. Hartmut Wekerle is in the Hertie Senior Professor Group, Max Planck Institute of Neurobiology, 82152 Martinsried, Germany.,

    Hartmut Wekerle

  2. Edgar Meinl is at the Institute of Clinical Neuroimmunology, LMU Munich, 81377 Munich, Germany.,

    Edgar Meinl

Authors
  1. Hartmut Wekerle
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  2. Edgar Meinl
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Corresponding author

Correspondence to Hartmut Wekerle.

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Wekerle, H., Meinl, E. An old drug plays a new trick. Nature 502, 314–315 (2013). https://doi.org/10.1038/nature12694

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