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Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q

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References

  1. Van den Berghe H, Cassiman JJ, David G, Fryns JP, Michaux JL, Sokal G . Distinct haematological disorder with deletion of long arm of no. 5 chromosome. Nature 1974; 251: 437–438.

    Article  CAS  PubMed  Google Scholar 

  2. Dewald GW, Davis MP, Pierre RV, O'Fallon JR, Hoagland HC . Clinical characteristics and prognosis of 50 patients with a myeloproliferative syndrome and deletion of part of the long arm of chromosome 5. Blood 1985; 66: 189–197.

    CAS  PubMed  Google Scholar 

  3. Boultwood J, Lewis S, Wainscoat JS . The 5q− syndrome. Blood 1994; 84: 3253–3260.

    CAS  PubMed  Google Scholar 

  4. Mathew P, Tefferi A, Dewald GW, Goldberg SL, Su J, Hoagland HC et al. The 5q− syndrome: a single-institution study of 43 consecutive patients. Blood 1993; 81: 1040–1045.

    CAS  PubMed  Google Scholar 

  5. Giagounidis AA, Germing U, Haase S, Hildebrandt B, Schlegelberger B, Schoch C et al. Clinical, morphological, cytogenetic, and prognostic features of patients with myelodysplastic syndromes and del(5q) including band q31. Leukemia 2004; 18: 113–119.

    Article  CAS  PubMed  Google Scholar 

  6. Brunning RD, Bennett JM, Flandrin G, Matutes E, Head D, Vardiman JW et al. Myelodysplastic syndrome associated with isolated del(5q) chromosome abnormality (‘5q− syndrome’). Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues: WHO Classification of Tumours. IARC Press: Lyons, France, 2001, pp 73–73.

    Google Scholar 

  7. Seo IS, Li CY, Yam LT . Myelodysplastic syndrome: diagnostic implications of cytochemical and immunocytochemical studies. Mayo Clin Proc 1993; 68: 47–53.

    Article  CAS  PubMed  Google Scholar 

  8. Santana-Davila R, Tefferi A, Holtan SG, Ketterling RP, Dewald GW, Knudson RA et al. Primary myelofibrosis is the most frequent myeloproliferative neoplasm associated with del(5q): Clinicopathologic comparison of del(5q)-positive and -negative cases. Leuk Res 2008; 32: 1927–1930.

    Article  CAS  PubMed  Google Scholar 

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Chen, D., Hoyer, J., Ketterling, R. et al. Dysgranulopoiesis is an independent adverse prognostic factor in chronic myeloid disorders with an isolated interstitial deletion of chromosome 5q. Leukemia 23, 796–800 (2009). https://doi.org/10.1038/leu.2008.279

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