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Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL

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References

  1. Falini B . Anaplastic large-cell lymphoma: pathological, molecular and clinical features. Br J Haematol 2001; 114: 741–760.

    Article  CAS  Google Scholar 

  2. Pulford K, Falini B, Banham AH, Codrington D, Roberton H, Hatton C et al. Immune response to the ALK oncogenic tyrosine kinase in patients with anaplastic large-cell lymphoma. Blood 2000; 96: 1605–1607.

    CAS  PubMed  Google Scholar 

  3. Mussolin L, Pillon M, d’Amore SG, Santoro N, Lombardi A, Fagioli F et al. Prevalence and clinical implications of bone marrow involvement in pediatric anaplastic large-cell lymphoma. Leukemia 2005; 19: 1643–1647.

    Article  CAS  Google Scholar 

  4. Damm-Welk C, Busch K, Burkhardt B, Schieferstein J, Viehmann S, Oschlies I et al. Prognostic significance of circulating tumor cells in bone marrow or peripheral blood as detected by qualitative and quantitative PCR in pediatric NPM-ALK-positive anaplastic large-cell lymphoma. Blood 2007; 110: 670–677.

    Article  CAS  Google Scholar 

  5. Brugieres L, Le Deley MC, Rosolen A, Williams D, Horibe K, Wrobel G et al. Anaplastic large cell lymphoma (ALCL) in children: equal efficacy but greater toxicity of chemotherapy including methotrexate (MTX) 1g/m2 in 24 hour infusion with intra-thecal injection (IT) than chemotherapy with MTX 3g/m2 in 3 hours infusion without IT: results of the ALCL99-R1 randomised trial[abstract]. Blood 2006; 108: 122a.

    Google Scholar 

  6. Gabert J, Beillard E, van der Velden VH, Bi W, Grimwade D, Pallisgaard N et al. Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion transcripts for residual disease detection in leukaemia—a Europe Against Cancer program. Leukemia 2003; 17: 2318–2357.

    Article  CAS  Google Scholar 

  7. Ait-Tahar K, Bernardo MCN, Pulford K . CD4 T-Helper responses to the anaplastic lymphoma kinase (ALK) protein in patients with ALK-positive anaplastic large-cell lymphoma. Cancer Res 2007; 67: 1898–1901.

    Article  CAS  Google Scholar 

  8. Passoni L, Gallo B, Biganzoli E, Stefanoni R, Massimino M, Di Nicola N et al. In vivo T-cell immune response against anaplastic lymphoma kinase in patients with anaplastic large-cell lymphomas. Haematologica 2006; 91: 48–55.

    CAS  PubMed  Google Scholar 

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Acknowledgements

This work was supported by Fondazione Città della Speranza.

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Authors and Affiliations

  1. Dipartimento di Pediatria, Clinica di Oncoematologia Pediatrica, Azienda Ospedaliera, Università di Padova, Padua, Italy

    L Mussolin, M Pillon, G Tridello & A Rosolen

  2. IOV (Istituto Oncologico Veneto-IRCCS, Padova), Padua, Italy

    P Bonvini

  3. Nuffeld Department of Clinical Laboratory Sciences, John Radcliffe Hospital, Oxford, UK

    K Ait-Tahar & K Pulford

  4. Dipartimento di Pediatria, Unità di Emato-oncologia Pediatrica, Ospedale Pausilipon, Naples, Italy

    S Buffardi

  5. Dipartimento di Pediatria, Clinica di Ematologia Pediatrica, Ospedale Bambino Gesù, Rome, Italy

    A Lombardi

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  1. L Mussolin
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  2. P Bonvini
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  3. K Ait-Tahar
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  4. M Pillon
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  5. G Tridello
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  6. S Buffardi
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  7. A Lombardi
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  8. K Pulford
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  9. A Rosolen
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Correspondence to A Rosolen.

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Mussolin, L., Bonvini, P., Ait-Tahar, K. et al. Kinetics of humoral response to ALK and its relationship with minimal residual disease in pediatric ALCL. Leukemia 23, 400–402 (2009). https://doi.org/10.1038/leu.2008.184

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