Skip to main content
SpringerLink
Log in

Hypovolaemia-induced mild hypoxia produces subchronic metabolic dysfunction

  • Letter to the Editor
  • Published:
International Journal of Obesity Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Ye J . Emerging role of adipose tissue hypoxia in obesity and insulin resistance. Int J Obes (Lond) 2009; 33: 54–66.

    Article  CAS  Google Scholar 

  2. Kabon B, Nagele A, Reddy D, Eagon C, Fleshman JW, Sessler DI et al. Obesity decreases perioperative tissue oxygenation. Anesthesiology 2004; 100: 274–280.

    Article  Google Scholar 

  3. Arkiliç CF, Taguchi A, Sharma N, Ratnaraj J, Sessler DI, Read TE et al. Supplemental perioperative fluid administration increases tissue oxygen pressure. Surgery 2003; 133: 49–55.

    Article  Google Scholar 

  4. Henriksen EJ . Improvement of insulin sensitivity by antagonism of the renin-angiotensin system. Am J Physiol Regul Integr Comp Physiol 2007; 293: R974–R980.

    Article  CAS  Google Scholar 

  5. Nangaku M, Fujita T . Activation of the renin-angiotensin system and chronic hypoxia of the kidney. Hypertens Res 2008; 31: 175–184.

    Article  Google Scholar 

  6. Dunn A, Lo V, Donnelly S . The role of the kidney in blood volume regulation: the kidney as a regulator of the hematocrit. Am J Med Sci 2007; 334: 65–71.

    Article  CAS  Google Scholar 

  7. Kim JW, Tchernyshyov I, Semenza GL, Dang CV . HIF-1-mediated expression of pyruvate dehydrogenase kinase: a metabolic switch required for cellular adaptation to hypoxia. Cell Metab 2006; 3: 177–185.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Université Henri Poincaré, U 961 UHP-INSERM, Risque cardiovasculaire, rigiditi-fibrose et hypercoagulabiliti Bbt. D, ler itage, Faculti de Midecine, B.P. 184-54505 VAND UVRE Les Nancy, Cedex, France. E-mail: simon.thornton@nancy.inserm.fr,

    S N Thornton

Authors
  1. S N Thornton
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Thornton, S. Hypovolaemia-induced mild hypoxia produces subchronic metabolic dysfunction. Int J Obes 33, 605 (2009). https://doi.org/10.1038/ijo.2009.26

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ijo.2009.26

  • Springer Nature Limited

This article is cited by

Search

Navigation