Skip to main content

Advertisement

Log in

Late onset of EBV-driven PTLD/Burkitt lymphoma/leukemia in a patient 10 years after allogeneic stem cell transplant for AML

  • Letter to the Editor
  • Published:
Bone Marrow Transplantation Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1
Figure 2

References

  1. Swerdlow SH, Webber SA, Chadburn A, Ferry JA . Post-transplant lymphoproliferative disorders. In: Swerdlow S, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H et al. (eds). World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tiussues. IARC Press: Lyon, 2008, pp 343–349.

    Google Scholar 

  2. Nalesnik MA, Jaffe R, Starzl TE, Demetris AJ, Porter K, Burnham JA et al. The pathology of post transplant lymphoproliferative disorders occurring in the setting of cyclosporine A-prednisone immunosuppression. Am J Pathol 1988; 133: 173–192.

    CAS  PubMed  PubMed Central  Google Scholar 

  3. Ocheni S, Kroeger N, Zabelina T, Sobottka I, Ayuk F, Wolschke C et al. EBV reactivation and post transplant lymphoproliferative disorders following allogeneic SCT. Bone Marrow Transplant 2008; 42: 181–186.

    Article  CAS  PubMed  Google Scholar 

  4. Weinstock DM, Ambrossi GG, Brennan C, Kiehn TE, Jakubowski A . Preemptive diagnosis and treatment of Epstein-Barr virus-associated post transplant lymphoproliferative disorder after hematopoietic stem cell transplant: an approach in development. Bone Marrow Transplant 2006; 37: 539–546.

    Article  CAS  PubMed  Google Scholar 

  5. Swinnen LJ, Costanzo-Nordin MR, Fisher SG, O'Sullivan EJ, Johnson MR, Heroux AL et al. Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac-transplant recipients. N Engl J Med 1990; 323: 1723–1728.

    Article  CAS  PubMed  Google Scholar 

  6. Loren W, Porter DL, Stadtmauer EA, Tsai DE . Post-transplant lymphoproliferative disorder: a review. Bone Marrow Transplantation 2003; 31: 145–155.

    Article  CAS  PubMed  Google Scholar 

  7. Bechtel D, Kurth J, Unkel C, Kuppers R . Transformation of BCR-deficient germinal-center B cells by EBV supports a major role of the virus in the pathogenesis of Hodgkin and posttransplantation lymphomas. Blood 2005; 106: 4345–4350.

    Article  CAS  PubMed  Google Scholar 

  8. Cohen JM, Cooper N, Chakrabarti S, Thomson K, Samarasinghe S, Cubitt D et al. EBV-related disease following haematopoietic stem cell transplantation with reduced intensity conditioning. Leuk Lymphoma 2007; 48: 256–269.

    Article  PubMed  Google Scholar 

  9. d'Amore ES, Manivel JC, Gajl-Peczalska KJ, Litz CE, Copenhaver CM, Shapiro RS et al. B-cell lymphoproliferative disorders after bone marrow transplant. An analysis of ten cases with emphasis on Epstein-Barr virus detection by in situ hybridization. Cancer 1991; 68: 1285–1295.

    Article  CAS  PubMed  Google Scholar 

  10. Bonagura VR, Katz BZ, Edwards BL, Valacer DJ, Nisen P, Gloster E et al. Severe chronic EBV infection associated with specific EBV immunodeficiency and an EBNA+ T-cell lymphoma containing linear, EBV DNA. Clin Immunol Immunopathol 1990; 57: 32–44.

    Article  CAS  PubMed  Google Scholar 

  11. Dehee A, Asselot C, Piolot T, Jacomet C, Rozenbaum W, Vidaud M et al. Quantification of Epstein-Barr virus load in peripheral blood of human immunodeficiency virus-infected patients using real-time PCR. J Med Virol 2001; 65: 543–552.

    Article  CAS  PubMed  Google Scholar 

  12. Leoncini L, Raphael M, Stein H, Harris NL, Jaffe ES, Kluin PM . Burkitt lymphoma. In: Swerdlow S, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H et al. (eds). World Health Organizaion Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tiussues. IARC Press: Lyon, 2008, 262–264.

    Google Scholar 

  13. Foucar K . Acute lymphoblastic leukemia. In: Foucar K (ed). Bone Marrow Pathology. ASCP: Chicago, 2001, pp 484–514.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Q Huang.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Huang, Q., Popplewell, L., Lu, Y. et al. Late onset of EBV-driven PTLD/Burkitt lymphoma/leukemia in a patient 10 years after allogeneic stem cell transplant for AML. Bone Marrow Transplant 45, 191–194 (2010). https://doi.org/10.1038/bmt.2009.86

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/bmt.2009.86

  • Springer Nature Limited

This article is cited by

Navigation