Abstract
Stearic acid and iodo-stearic and inhibited cell growth in a cervical cancer cell line (HOG-1) in a dose-related manner, with a half maximal effect at 50 microM stearic acid. Addition of oleic acid abrogated the effect of stearic acid. EGF-stimulated DNA synthesis and growth of HOG-1 cells was inhibited in the presence of stearic acid without any apparent effect on EGF receptor number or affinity.
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Gleeson, R., Ayub, M., Wright, J. et al. Fatty acid control of growth of human cervical and endometrial cancer cells. Br J Cancer 61, 500–503 (1990). https://doi.org/10.1038/bjc.1990.113
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DOI: https://doi.org/10.1038/bjc.1990.113
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