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DNA polymerase activity in plasma from leukaemic guinea-pigs

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Abstract

Measurement of DNA polymerase in leukaemic guinea-pig plasms reveals the presence of low levels of sedimentable and non-sedimentable enzymic activities. Since the sedimentable DNA polymerase is ribonuclease sensitive, uses poly(C).oligo(dG) as template, and bands in a sucrose density gradient at 1-17 g/ml it is thought to be the GPLV-associated reverse transcriptase. The soluble DNA polymerase is stimulated by ribonuclease and is probably of cellular origin.

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Authors
  1. F M Hallinan
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  2. N Maclean
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Hallinan, F., Maclean, N. DNA polymerase activity in plasma from leukaemic guinea-pigs. Br J Cancer 33, 419–426 (1976). https://doi.org/10.1038/bjc.1976.67

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  • DOI: https://doi.org/10.1038/bjc.1976.67

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