Abstract
Conversion of 7alpha3H-testosterone to 17beta-oestradiol by human mammary carcinoma tissue in vitro has been demonstrated. It was characterized unequivocally by conversion to 17beta-oestradiol-3-sulphate upon incubation with adenosine-3'-phosphate-5'-phosphosulphate and the highly specific enzyme oestrogen sulphotransferase.
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Adams, J., Li, K. Biosynthesis of 17β-oestradiol in human breast carcinoma tissue and a novel method for its characterization. Br J Cancer 31, 429–433 (1975). https://doi.org/10.1038/bjc.1975.82
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DOI: https://doi.org/10.1038/bjc.1975.82
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