Abstract
Nineteen cases of malignant lymphomata were selected for study from a group of about 1500 collected cases of malignant lymphomata because they showed histological evidence of non-infectious epithelioid-cell granulomata in one or more tissues.
In the 19 cases selected, 5 cases of systemic sarcoidosis, 4 cases of an associated malignancy, 1 pre-malignant condition, and 1 case of an auto-immune disease were found.
This remarkable association of sarcoid reactions or sarcoidosis with malignant lymphomata and associated malignancies seems to justify speculation on the possibility of a common aetiological factor, e.g. in the form of an altered immune reaction.
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Brincker, H. Sarcoid Reactions and Sarcoidosis in Hodgkin's Disease and Other Malignant Lymphomata. Br J Cancer 26, 120–128 (1972). https://doi.org/10.1038/bjc.1972.18
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DOI: https://doi.org/10.1038/bjc.1972.18
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