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Beam me up, Scottie! TREK channels swing both ways

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TREK1 was known as a voltage-independent 'background' potassium channel, but a new study suggests that protein kinase A can reversibly convert it to a voltage-dependent state.

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Figure 1: At rest (left), unphosphorylated TREK1 channels help set the resting membrane potential.

Bob Crimi

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Authors and Affiliations

  1. Vollum Institute,

    James Maylie & John P. Adelman

  2. Obstetrics and Gynecology Dept.,Oregon Health Sciences University, 3181 S.W. Sam Jackson Park Rd., Portland, 97201-3098, Oregon, USA

    James Maylie & John P. Adelman

Authors
  1. James Maylie
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  2. John P. Adelman
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Maylie, J., Adelman, J. Beam me up, Scottie! TREK channels swing both ways. Nat Neurosci 4, 457–458 (2001). https://doi.org/10.1038/87402

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