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Calcium channel splicing: mind your Ps and Qs

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Abstract

Bourinet and colleagues show that combinations of P- and Q-like characteristics can arise through alternative splicing of a single gene encoding the calcium channel α1A subunit.

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Figure 1: Schematic structure of the pore-forming (α1) subunit of voltage-gated calcium channels, showing two regions affected by alternative splicing.

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Authors and Affiliations

  1. Department of Anatomy and Neurobiology, Colorado State University, Fort Collins, 80523, Colorado, USA

    Kurt Beam

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  1. Kurt Beam
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Beam, K. Calcium channel splicing: mind your Ps and Qs. Nat Neurosci 2, 393–394 (1999). https://doi.org/10.1038/8052

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