Abstract
By globally cataloging cellular protein content and state, proteomics promises to complement genomics in drug discovery and basic research.
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References
Edman, P. Acta Chem. Scand. 4, 282–283 (1950).
Barret, T. & Gould, J. Biochem. Biophys. Acta 294, 165–170 (1973).
O'Farrell, P.H. J. Biol. Chem. 250, 4007–4021 (1975).
Wasinger V.C. et al. Electrophoresis 16, 1090– 1094 (1995).
Fleischmann, R.D. et al. Science 269, 496–512 (1995).
James, P. Biochem. Biophys. Res. Comm. 231, 1– 6 (1997).
Klose, J. & Kobalz, U. Electrophoresis 16, 1034–1059 (1995).
Vorm, O. & Mann, M. J. Am. Mass Spec. 5, 955–958 (1994).
Henzel W.J. et al. Proc. Natl. Acad. Sci. USA 90, 5011– 5015 (1993).
Taylor, J. et al. Clin. Chem. 28, 861–866 (1982).
SwissProt databases (http://expasy.hcuge.ch).
Yates, J.R. et al. Anal. Biochem. 214, 397–408 (1993).
Humphery-Smith I. et al. Electrophoresis 18, 1217– 1242 (1997).
Yates, J.R. J. Mass Spec. 33, 1–19 ( 1998).
Moult, J. & Melamud, E. Curr. Opin. Struct. Biol. 10, 384-389 (2000).
Gerstein, M. et al. Pac. Symp. Biocomput. 12, 30– 41 (2000).
Cordwell, S.J. et al. Electrophoresis 21, 1094– 1103 (2000).
Haynes, P.A. & Yates, J.R. Yeast 17, 81–87 (2000).
Gygi, S.P. et al. Nat. Biotechnol. 17, 994–999 (1999)
Link, A.J. et al. Nat. Biotechnol. 17, 676–682 (1999).
Locke, S. & Figeys, D. Anal. Chem. 72, 2684–2689 (2000).
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Proteomics. Nat Biotechnol 18 (Suppl 10), IT45–IT46 (2000). https://doi.org/10.1038/80085
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DOI: https://doi.org/10.1038/80085
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