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Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling

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A Correction to this article was published on 01 December 2000

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Figure 1: Detection and functional analysis of AXIN2 mutations in CRC with defective MMR.

References

  1. Marra, G. & Boland, C.R. J. Natl Cancer Inst. 87, 1114–1125 (1995).

    Article  CAS  PubMed  Google Scholar 

  2. Mai, M. et al. Genomics 55, 341–344 (1999).

    Article  CAS  PubMed  Google Scholar 

  3. Behrens, J. et al. Science 280, 596–599 (1998).

    Article  CAS  PubMed  Google Scholar 

  4. Liu, W. et al. Nucleic Acids Res. 26, 1396–1400 (1998).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. Boland, C.R. et al. Cancer Res. 58, 5248–5257 (1998).

    CAS  PubMed  Google Scholar 

  6. Chan, E.F. et al. Nature Genet. 21, 410–413 (1999).

    Article  CAS  PubMed  Google Scholar 

  7. Ganguly, A. et al. Proc. Natl Acad. Sci. USA 90, 10325–10329 (1993).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  8. Powell, S.M. et al. N. Engl. J. Med. 329, 1982–1987 (1993).

    Article  CAS  PubMed  Google Scholar 

  9. Ishitani, T. et al. Nature 399, 798–802 (1999).

    Article  CAS  PubMed  Google Scholar 

  10. Rampino, N. et al. Science 275, 967–969 (1997).

    Article  CAS  PubMed  Google Scholar 

  11. Miyashita, T. & Reed, J.C. Cell 80, 293–299 (1995).

    Article  CAS  PubMed  Google Scholar 

  12. Peifer, M. & Polakis, P. Science 287, 1606–1609 (2000).

    Article  CAS  PubMed  Google Scholar 

  13. Kishida, S. et al. Mol. Cell. Biol. 19, 4414–4422 (1999).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  14. Satoh, S. et al. Nature Genet. 24, 245–250 (2000).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

These studies were carried out with the support of funds from Mayo Clinic/Foundation to W.L. and by grants from the National Institutes of Health to D.I.S. (CA 48031) and S.N.T. (CA 60117).

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Correspondence to Wanguo Liu.

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Liu, W., Dong, X., Mai, M. et al. Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating β-catenin/TCF signalling. Nat Genet 26, 146–147 (2000). https://doi.org/10.1038/79859

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