Less than 20 years after the first biopharmaceutical, insulin, was approved, a new generation of products is superseding replacement proteins and enzyme therapies in biotechnology's pipeline.
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Walsh, G. Biopharmaceutical benchmarks. Nat Biotechnol 18, 831–833 (2000). https://doi.org/10.1038/78720
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DOI: https://doi.org/10.1038/78720
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