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New tricks from an itinerant intron

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A new mechanism for transposition by autocatalytic group II introns provides a working model for intron dispersal in eukaryotic genomes.

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Figure 1: Splicing of group II introns is a reversible, two-step process.
Figure 2: Two pathways for retrotransposition of group II introns in Lactococcus lactis:

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Acknowledgements

I wish to thank Q. Xiang, T. Bestor and P. Pang for their helpful comments on this manuscript and N. Craig for information on transposon abundance.

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Authors and Affiliations

  1. the Department of Biochemistry and Molecular Biophysics and the Howard Hughes Medical Institute, Columbia University,

    Anna Marie Pyle

  2. New York, 10027, NY, USA

    Anna Marie Pyle

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Pyle, A. New tricks from an itinerant intron. Nat Struct Mol Biol 7, 352–354 (2000). https://doi.org/10.1038/75111

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