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Getting a foothold in nephrotic syndrome

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The podocyte is a highly specialized kidney cell that is essential to the ultrafiltration of blood, resulting in the extraction of urine and the retention of protein. Four studies, the most recent of which is published in this issue of Nature Genetics, indicate its critical role in the pathology of nephrotic syndrome.

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Figure 1: The structure of the glomerulus.
Figure 2: Glomerular ultrastructure.
Figure 3: Molecular anatomy of the podocyte foot process cytoskeleton.

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Authors and Affiliations

  1. Section of Nephrology, Yale University School of Medicine , 295 Congress Avenue, New Haven, 06536, Connecticut , USA

    Stefan Somlo

  2. Division of Nephrology, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, 10461, New York, USA

    Peter Mundel

Authors
  1. Stefan Somlo
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  2. Peter Mundel
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Somlo, S., Mundel, P. Getting a foothold in nephrotic syndrome. Nat Genet 24, 333–335 (2000). https://doi.org/10.1038/74139

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