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Do all SINEs lead to LINEs?

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More than 30% of the human genome consists of retroposed sequences—including retroposons and processed genes—but retroposition events are rare. New experimental methods that accelerate retroposition are now clarifying the mechanisms that shape the genome.

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Figure 1: LINE elements and their presumed dependents.
Figure 2: LINE reverse transcriptase generates processed genes.

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  1. Department of Molecular Biophysics and Biochemistry, Yale University School of Medicine, 333 Cedar Street, New Haven, 06520, Connecticut, USA

    Alan M Weiner

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  1. Alan M Weiner
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Weiner, A. Do all SINEs lead to LINEs?. Nat Genet 24, 332–333 (2000). https://doi.org/10.1038/74135

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