Skip to main content
Log in

Generation of mice from wild-type and targeted ES cells by nuclear cloning

  • Brief Communication
  • Published:

From Nature Genetics

View current issue Submit your manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Figure 1: Targeted insertion at the ROSA26 locus in cloned mice.

References

  1. Baguisi, A. et al. Nature Biotechnol. 17, 456–461 (1999).

    Article  CAS  Google Scholar 

  2. Kato, Y. et al. Science 282, 2095–2098 (1998).

    Article  CAS  PubMed  Google Scholar 

  3. Wells, D.N., Misica, P.M. & Tervit, H.R. Biol. Reprod. 60, 996–1005 (1999).

    Article  CAS  PubMed  Google Scholar 

  4. Wilmut, I., Schnieke, A.E., McWhir, J., Kind, A.J. & Campbell, K.H. Nature 385, 810–813 (1997).

    Article  CAS  PubMed  Google Scholar 

  5. Wakayama, T., Perry, A.C., Zuccotti, M., Johnson, K.R. & Yanagimachi, R. Nature 394, 369–374 (1998).

    Article  CAS  PubMed  Google Scholar 

  6. Campbell, K.H., Loi, P., Otaegui, P.J. & Wilmut, I. Rev. Reprod. 1, 40–46 (1996).

    Article  CAS  PubMed  Google Scholar 

  7. Wakayama, T. & Yanagimachi, R. Nature Genet. 22, 127–128 (1999).

    Article  CAS  PubMed  Google Scholar 

  8. Wakayama, T., Rodriguez, I., Perry, A.C., Yanagimachi, R. & Mombaerts, P. Proc. Natl Acad. Sci. USA 96, 14984–14989 (1999).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  9. Simpson, E.M. et al. Nature Genet. 16, 19–27 (1997).

    Article  CAS  PubMed  Google Scholar 

  10. Dean, W. et al. Development 125, 2273–2282 (1998).

    CAS  PubMed  Google Scholar 

  11. Soriano, P. Nature Genet. 21, 70–71 (1999).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

We thank H. Bujard for the rtTA2 construct. This work was supported by a grant from the NIH.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rudolf Jaenisch.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Rideout, W., Wakayama, T., Wutz, A. et al. Generation of mice from wild-type and targeted ES cells by nuclear cloning. Nat Genet 24, 109–110 (2000). https://doi.org/10.1038/72753

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/72753

  • Springer Nature America, Inc.

This article is cited by

Navigation