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A dynamic duo of microtubule modulators

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Abstract

Microtubule dynamics are regulated by a diverse array of factors. The net balance of two opposing activities largely determines microtubule length throughout the cell cycle.

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Figure 1: XMAP215 and XKCM1 have antagonistic effects on microtubule length and catastrophe frequency.
Figure 2: Shrink globally, act locally.

References

  1. Tournebize, R. et al. Nature Cell Biol. 2, 13– 19 (2000).

    Article  CAS  Google Scholar 

  2. Desai, A. & Mitchison, T. J. Annu. Rev. Cell Dev. Biol. 13, 83–117 ( 1997).

    Article  CAS  Google Scholar 

  3. Cassimeris, L. Curr. Opin. Cell Biol. 11, 134–141 (1999).

    Article  CAS  Google Scholar 

  4. Belmont, L. D., Hyman, A. A., Sawin, K. E. & Mitchison, T. J. Cell 62, 579–589 ( 1990).

    Article  CAS  Google Scholar 

  5. Gard, D. L. & Kirschner, M. W. J. Cell Biol. 105 , 2203–2215 (1987).

    Article  CAS  Google Scholar 

  6. Vasquez, R. J., Gard, D. L. & Cassimeris, L. J. Cell Biol. 127, 985– 993 (1994).

    Article  CAS  Google Scholar 

  7. Walczak, C. E., Mitchison, T. J. & Desai, A. Cell 84, 37– 47 (1996).

    Article  CAS  Google Scholar 

  8. Desai, A., Verma, S., Mitchison, T. J. & Walczak, C. E. Cell 96, 69–78 ( 1999).

    Article  CAS  Google Scholar 

  9. Vasquez, R. J., Gard, D. L. & Cassimeris, L. Cell Motil. Cytoskel. 43, 310 –321 (1999).

    Article  CAS  Google Scholar 

  10. Karsenti, E. Semin. Cell Biol. 2, 251–260 (1991).

    CAS  PubMed  Google Scholar 

  11. Andersen, S. S. L. Bioessays 21, 53–60 ( 1999).

    Article  CAS  Google Scholar 

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Authors and Affiliations

  1. the Department of Molecular & Cell Biology, University of California, Berkeley, 94720-3200, California, USA

    Rebecca Heald

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  1. Rebecca Heald
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Heald, R. A dynamic duo of microtubule modulators. Nat Cell Biol 2, E11–E12 (2000). https://doi.org/10.1038/71394

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